Kisspeptin signaling in reproductive biology /
Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet know...
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| Kolejni autorzy: | , |
| Format: | E-book |
| Język: | English |
| Wydane: |
New York, NY
Springer New York
2013.
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| Seria: | Advances in Experimental Medicine and Biology
784 |
| Hasła przedmiotowe: | |
| Dostęp online: | Click here to view the full text content |
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| Streszczenie: | Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis. |
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| Opis fizyczny: | 1 online resource (XII, 514 pages) 100 illustration, 58 illustration in colour. |
| ISBN: | 9781461461999 |
| ISSN: | 0065-2598 |