RNA 3D structure analysis and prediction /

<p>With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the hu...

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Detalhes bibliográficos
Autor Corporativo: SpringerLink (Online service)
Outros Autores: Westhof, Eric, Leontis, Neocles
Formato: livro electrónico
Idioma:English
Publicado em: Berlin, Heidelberg Springer Berlin Heidelberg 2012.
Colecção:Nucleic acids and molecular biology 27
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Descrição
Resumo:<p>With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone.  This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches. </p>
Descrição Física:1 online resource (X, 400 pages) 115 illustration., 80 illustration. in colour. digital.
ISBN:9783642257407
ISSN:0933-1891