RNA metabolism in trypanosomes /

<p>Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped...

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书目详细资料
企业作者: SpringerLink (Online service)
其他作者: Bindereif, Albrecht
格式: 电子书
语言:English
出版: Berlin, Heidelberg Springer Berlin Heidelberg 2012.
丛编:Nucleic Acids and Molecular Biology 28
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总结:<p>Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most important aspects of biosynthesis, processing, and functions of RNA in trypanosomes, ranging from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA, RNA interference, and current transcriptome-wide analyses. Recent progress in RNA-focused research in trypanosomatids promises to yield novel insights into trypanosome-specific features, as well as to reveal in the process new potential therapeutic strategies for combating these parasitic diseases. </p>
实物描述:1 online resource (VI, 271 pages) 27 illustration, 22 illustration in colour, digital.
ISBN:9783642286872
ISSN:0933-1891