Nuclear Reprogramming and Stem Cells
<p>Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mecha...
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| Formato: | livro electrónico |
| Idioma: | English |
| Publicado em: |
Totowa, NJ :
Humana Press,
2012.
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| Edição: | 1. |
| Colecção: | Stem Cell Biology and Regenerative Medicine
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| Acesso em linha: | Click here to view the full text content |
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Sumário:
- <p>Introduction by John Gurdon and Azim Surani
- Introduction by Ian Wilmut
- Inherent Nuclear Reprogramming in Mammalian Embryos
- Epigenetic Reprogramming During Somatic Cell Nuclear Transfer and the Development of Primordial Germ Cells
- Epigenetic Reprogramming with Oocyte Molecules
- Cell Fusion-Mediated Nuclear Reprogramming of Somatic Cells
- Generation of Induced Pluripotent Stem Cells from Somatic Cells
- The Consequences of Reprogramming a Somatic Cell for Mitochondrial DNA Transmission, Inheritance and Replication
- The Function of Nanog in Pluripotency
- The Function of Oct3/4 and Sox2 in Pluripotency
- Generation of Neural Cells from Pluripotent Stem Cells
- Non-Cell Autonomous Reprogramming Towards a Pluripotent State
- Towards Regeneration of Retinal Function Using Pluripotent Stem Cells
- Reprogramming Towards Pancreatic beta-Cells
- Pancreatic Plasticity and Reprogramming - Novel Directions Towards Disease Therapy
- Phenotype and Developmental Potential of Cardiomyocytes from Induced Pluripotent Stem Cells and Human Embryonic Stem Cells
- The Generation of Disease Specific Cell Lines and Their Use for Developing Drug Therapies
- Advances in the Culture of Human Embryonic Stem Cells
- Culture adaptation of pluripotent stem cells: challenges and opportunities
- Epilogue.</p>.