Characterization of protein therapeutics using mass spectrometry /

Protein therapeutics' high efficacy, safety, and ability to treat life-threatening diseases such as cancer, inflammation and genetic disorders have revolutionized modern medicine. In 2012, 200 companies competed in this $90 billion year industry.   In Characterization of Protein Therapeutics us...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Boston, MA Springer US Imprint: Springer, 2013.
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Table of Contents:
  • Characterization of Protein Therapeutics by Mass Spectrometry: Recent Developments and Future Directions
  • The Use of Mass Spectrometry to Characterize the Metabolism of Peptide Therapeutics
  • Quantitative Analysis of Biologics Using Mass Spectrometry
  • Maximizing Structural Information from Whole Protein Tandem Mass Spectrometry
  • Disulfide Linkages of an Albumin Fusion Protein
  • Detailed Structural Characterization of Monoclonal Antibodies
  • Application of Protein Mass Spectrometry in Impurity and Degradant Characterization
  • Mass Spectrometry Methods to Analyze Higher Order Structure of Protein Therapeutics by Chemical Footprinting
  • Aglycosylations Alters Protein Conformation in Antibodies Engineered with Specific Effector Functions Using HDX-MS
  • Characterizing Biotherapeutic Protein 3D Structures by Electrospray Ion-Mobility Mass Spectrometry
  • Oxford University, Characterization of Assemblies of Proteins by Mass Spectrometry.