Untranslated gene regions and other non-coding elements : regulation of eukaryotic gene expression /
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation,...
Đã lưu trong:
| Tác giả chính: | |
|---|---|
| Tác giả của công ty: | |
| Tác giả khác: | , |
| Định dạng: | eBook |
| Ngôn ngữ: | English |
| Được phát hành: |
Basel
Springer Basel
2013.
|
| Loạt: | SpringerBriefs in Biochemistry and Molecular Biology
|
| Những chủ đề: | |
| Truy cập trực tuyến: | Click here to view the full text content |
| Các nhãn: |
Thêm thẻ
Không có thẻ, Là người đầu tiên thẻ bản ghi này!
|
| Tóm tắt: | There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution. |
|---|---|
| Mô tả vật lý: | 1 online resource (VIII, 56 pages) 2 illustration in colour. |
| số ISBN: | 9783034806794 |
| số ISSN: | 2211-9353 |