Untranslated gene regions and other non-coding elements : regulation of eukaryotic gene expression /
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation,...
Gorde:
| Egile nagusia: | |
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| Erakunde egilea: | |
| Beste egile batzuk: | , |
| Formatua: | eBook |
| Hizkuntza: | English |
| Argitaratua: |
Basel
Springer Basel
2013.
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| Saila: | SpringerBriefs in Biochemistry and Molecular Biology
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| Gaiak: | |
| Sarrera elektronikoa: | Click here to view the full text content |
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Etiketa erantsi
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| 100 | 1 | |a Barrett, Lucy W. |e author | |
| 245 | 1 | 0 | |a Untranslated gene regions and other non-coding elements : |b regulation of eukaryotic gene expression / |c by Lucy W. Barrett, Sue Fletcher, Steve D. Wilton. |
| 264 | 1 | |a Basel |b Springer Basel |c 2013. | |
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| 490 | 1 | |a SpringerBriefs in Biochemistry and Molecular Biology |x 2211-9353 | |
| 520 | |a There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution. | ||
| 650 | 0 | |a Life sciences. | |
| 650 | 0 | |a Medical genetics. | |
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| 650 | 0 | |a Plant breeding. | |
| 650 | 0 | |a Animal genetics. | |
| 700 | 1 | |a Fletcher, Sue. | |
| 700 | 1 | |a Wilton, Steve D. | |
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| 776 | 0 | 8 | |i Printed edition |z 9783034806787 |
| 830 | 0 | |a SpringerBriefs in Biochemistry and Molecular Biology |x 2211-9353 | |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/978-3-0348-0679-4 |y Click here to view the full text content |
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