Cholesterol and presynaptic glutamate transport in the brain /
Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders. Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced lev...
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| Autor principal: | |
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| Autor Corporativo: | |
| Formato: | livro eletrônico |
| Idioma: | English |
| Publicado em: |
New York, NY
Springer New York
2013.
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| coleção: | SpringerBriefs in Neuroscience
12 |
| Assuntos: | |
| Acesso em linha: | Click here to view the full text content |
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| Resumo: | Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders. Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced levels of cholesterol have been implicated in the pathogenesis of disorders such as stroke, ischemia, traumatic brain injury, and neurotoxicity. In the proposed book, the author presents data from the literature and from her own lab to address the extent to and way in which membrane cholesterol modulates presynaptic glutamate transport and whether lowering the level of cholesterol available can offer some neuroprotective benefits. |
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| Descrição Física: | 1 online resource (XVI, 75 pages) 32 illustration, 11 illustration in colour. |
| ISBN: | 9781461477594 |
| ISSN: | 2191-558X |