Cholesterol and presynaptic glutamate transport in the brain /

Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders.  Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced lev...

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Hlavní autor: Borisova, Tatiana (Autor)
Korporativní autor: SpringerLink (Online service)
Médium: E-kniha
Jazyk:English
Vydáno: New York, NY Springer New York 2013.
Edice:SpringerBriefs in Neuroscience 12
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Popis
Shrnutí:Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders.  Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced levels of cholesterol have been implicated in the pathogenesis of disorders such as stroke, ischemia, traumatic brain injury, and neurotoxicity.   In the proposed book, the author presents data from the literature and from her own lab to address the extent to and way in which membrane cholesterol modulates presynaptic glutamate transport and whether lowering the level of cholesterol available can offer some neuroprotective benefits.
Fyzický popis:1 online resource (XVI, 75 pages) 32 illustration, 11 illustration in colour.
ISBN:9781461477594
ISSN:2191-558X