Sphingolipids : basic science and drug development /

Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipi...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Petrache, Irina, Gulbins, Erich
Format: eBook
Language:English
Published: Vienna Springer Vienna 2013.
Series:Handbook of Experimental Pharmacology 215
Subjects:
Online Access:Click here to view the full text content
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Summary:Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids' basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.
Physical Description:1 online resource (VIII, 259 pages.) 90 illustrations., 30 illustrations. in colour. digital
ISBN:9783709113684
ISSN:0171-2004