Cancer genomics : molecular classification, prognosis and response prediction /
The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with i...
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| Định dạng: | eBook |
| Ngôn ngữ: | English |
| Được phát hành: |
Dordrecht
Springer Netherlands
2013.
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| Những chủ đề: | |
| Truy cập trực tuyến: | Click here to view the full text content |
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| Tóm tắt: | The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident. |
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| Mô tả vật lý: | 1 online resource (VI, 588 pages.) 65 illustrations., 61 illustrations. in colour. digital |
| số ISBN: | 9789400758421 |