Advancing methods for biomolecular crystallography /
This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to de...
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| Corporate Author: | |
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| Other Authors: | , , |
| Format: | eBook |
| Language: | English |
| Published: |
Dordrecht
Springer Netherlands
2013.
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| Series: | NATO Science for Peace and Security Series A: Chemistry and Biology,
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| Subjects: | |
| Online Access: | Click here to view the full text content |
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| Summary: | This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome. Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored. |
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| Physical Description: | 1 online resource (XIII, 362 pages.) 131 illustrations. digital |
| ISBN: | 9789400762329 |
| ISSN: | 1874-6489 |