Drug design : methodology, concepts, and mode-of-action /

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applicati...

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Збережено в:
Бібліографічні деталі
Співавтор: SpringerLink (Online service)
Інші автори: Klebe, Gerhard
Формат: eКнига
Мова:English
Опубліковано: Berlin, Heidelberg Springer Berlin Heidelberg 2013.
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Опис
Резюме:Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determination multiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.
Фізичний опис:1 online resource (XV, 901 pages) 496 illustration, 333 illustration in colour.
ISBN:9783642179075