Neuroanatomy and Pathology of Sporadic Alzheimer's Disease /

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. T...

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Bibliographic Details
Main Authors: Braak, Heiko (Author), Del Tredici, Kelly (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
Series:Advances in Anatomy, Embryology and Cell Biology, 215
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Online Access:Click here to view the full text content
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Table of Contents:
  • Prologue
  • General Morphology of Alzheimer-associated intraneuronal pathology
  • Consistent and systematic changes in the distribution pattern of intraneuronal inclusions render staging possible
  • Basic organization of involved structures
  • Presymptomatic stages
  • General morphology of Alzheimer-associated extracellular pathology
  • Symptomatic stages
  • The progression of cortical lesions mimics the pattern of myelination in reverse order
  • Tauopathies
  • CSF biomarkers and imaging techniques
  • The staging hypothesis: assumptions, challenges, potential
  • Technical considerations.   .