DNA topoisomerases and cancer/

DNA topoisomerases are present in all living organisms and are essential to maintaining the helical structure of DNA. They are highly relevant for cancer because a number of anti-cancer drugs selectively target two of the human enzymes, DNA topoisomerases I and II. Those drugs convert topoisomerases...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Pommier, Yves
Format: eBook
Language:English
Published: New York, NY Springer New York 2012.
Series:Cancer Drug Discovery and Development
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