Sex and gender differences in pharmacology /

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I co...

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Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Outros autores: Regitz-Zagrosek, Vera
Formato: eBook
Idioma:English
Publicado: Berlin, Heidelberg Springer Berlin Heidelberg 2012.
Series:Handbook of Experimental Pharmacology 214
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Descripción
Summary:This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.
Descrición Física:1 online resource (IX, 600 pages) 37 illustration, 22 illustration in colour, digital.
ISBN:9783642307263
ISSN:0171-2004