Nuclear Reprogramming and Stem Cells

Nuclear Reprogramming and Stem Cells

<p>Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mecha...

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Bibliographic Details
Main Author: Ainscough, Justin (Author)
Corporate Author: SpringerLink (Online service)
Other Authors: Yamanaka, Shinya, Tada, Takashi
Format: eBook
Language:English
Published: Totowa, NJ : Humana Press, 2012.
Edition:1.
Series:Stem Cell Biology and Regenerative Medicine
Subjects:
Life sciences.
Biotechnology.
Cytology.
Stem cells.
Online Access:Click here to view the full text content
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Table of Contents:
  • <p>Introduction by John Gurdon and Azim Surani
  • Introduction by Ian Wilmut
  • Inherent Nuclear Reprogramming in Mammalian Embryos
  • Epigenetic Reprogramming During Somatic Cell Nuclear Transfer and the Development of Primordial Germ Cells
  • Epigenetic Reprogramming with Oocyte Molecules
  • Cell Fusion-Mediated Nuclear Reprogramming of Somatic Cells
  • Generation of Induced Pluripotent Stem Cells from Somatic Cells
  • The Consequences of Reprogramming a Somatic Cell for Mitochondrial DNA Transmission, Inheritance and Replication
  • The Function of Nanog in Pluripotency
  • The Function of Oct3/4 and Sox2 in Pluripotency
  • Generation of Neural Cells from Pluripotent Stem Cells
  • Non-Cell Autonomous Reprogramming Towards a Pluripotent State
  • Towards Regeneration of Retinal Function Using Pluripotent Stem Cells
  • Reprogramming Towards Pancreatic beta-Cells
  • Pancreatic Plasticity and Reprogramming - Novel Directions Towards Disease Therapy
  • Phenotype and Developmental Potential of Cardiomyocytes from Induced Pluripotent Stem Cells and Human Embryonic Stem Cells
  • The Generation of Disease Specific Cell Lines and Their Use for Developing Drug Therapies
  • Advances in the Culture of Human Embryonic Stem Cells
  • Culture adaptation of pluripotent stem cells: challenges and opportunities
  • Epilogue.</p>.

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